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Mircera (methoxy polyethylene glycol-epoetin beta)is
a third generation version of erythropoietin manufactured
by pharmaceutical giant Hoffman-LaRoche that has
been called "Super EPO."
Mircera is an artificial form of erythropoietin
(EPO) stimulators similar to Amgen's Epogen and
Aranesp. But Mircera is thought to be superior to
Epogen and Aranesp due to the use of pegylation
technology that provides a sustained release of
erythropoiesis stimulating proteins (ESPs). PEGylated
erythropoietin (PEG-EPO) results when a molecule
of polyethylene glycol is attached.
Mircera (PEG-EPO) belongs to a category of drugs
called Continuous Erythropoeitin Receptor Activators
or CERA because it continuously interacts with the
EPO receptor producing longer lasting effects. Only
1-2 monthly injections of Mircera have similar results
to three times weekly injections of Epogen.
Cyclist Riccardo Ricco of
the Saunier Duval-Scott
professional cycling team
was the first athlete to
test positive for the new
performance enhancing drug
Mircera. His 'A' sample
tested positive for metabolites
of Mircera on July 17, 2008
at the 2008 Tour de France.
Download Mircera Package Insert
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Publication Date:
December 30, 2003
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