House, M.D., the medical television drama, discussed “roid rage” as a side effect of steroids last night in an episode entitled “No More Mr. Nice Guy.” The House medical team attributed the “roid rage” to the catabolic steroid prednisone. “Roid rage” is not a medical term, but a term arising from popular culture.

“Roid rage” is a typically used to described uncontrolled aggression exhibited in anabolic-androgenic steroids users. “Roid rage” has become an accepted side effect from anabolic steroids in spite of the lack of medical evidence documenting a direct effect of steroids on aggression.

Even though aggression in anabolic steroids users is rare, the producers of House decided to promote an even less plausible case of “roid rage” (arising from prednisone use). Then again, the whole point of the television show is to explore rare medical cases and consequently rare side effects. So, perhaps the reference to roid rage was consistent with the goals of the show rather than a capitulation to the current pop culture fascination with anabolic steroids and roid rage and related undocumented or overstated side effects of steroids?