An investigative series on anti-aging medicine by Brian Alexander of MSNBC is highly critical of the anti-aging industry. Alexander has interviewed a few academics to reinforce the skeptical overview of the industry suggesting the industry is more about financial profiteering than health optimization (”Mainstream docs join anti-aging bandwagon,” April 21).
Dr. Thomas Perls, a Boston University researcher who studies centenarians (people who live at least 100 years), and a vociferous critic of the anti-aging industry, argues that while some anti-aging practitioners “may have their hearts in the right place … in my mind the whole anti-aging practice has so many problems of ethical and professional misconduct. These practices are selling medicines and substances at great profit with very little in the way of clinical studies to support what they are doing.”
The answers to the science questions can be complicated, but the motivations of some doctors to enter the anti-aging world are not. Dr. Arnold Relman, a former editor of The New England Journal of Medicine who is now a professor emeritus of medicine and social medicine at Harvard Medical School, believes “the interest in anti-aging practice is mainly based on economic considerations” by physicians who are looking to boost income.
Alexander is troubled by the extreme commercialization of the anti-aging industry as seen at anti-aging conventions (”Selling longer life - or snake oil?” April 18).
Indeed, there is no better place to witness the truism of the phrase “hope springs eternal” — and perhaps “there’s a sucker born every minute” — than an anti-aging convention, especially on the trade show floor where the latest products and services are hawked.
At the 15th Annual World Congress on Anti-Aging and Regenerative Biomedical Technologies in Las Vegas, held under the auspices of the American Academy of Anti-Aging Medicine (A4M), dozens of businesses set up displays to market everything from horny goat weed dietary supplements to wands containing dirt that supposedly align water molecules so the H2O will get into your cells…
In an interview, Dr. Ronald Klatz, co-founder, with Dr. Bob Goldman, of A4M, said he gets annoyed when reporters wander the booths of an A4M event and use the sketchy claims and flimsy science of fringe products to attack the credibility of A4M or anti-aging in general.
“This exhibit hall is constantly being mistaken for the American Academy of Anti-Aging Medicine,” he said. “But that is just the exhibit hall. That is where advertising, lotions, potions, lasers, X-ray equipment, plastic surgery equipment are being sold. That is an exposition. That is advertising! Then there is the scientific conference. That is where the real science is going on and real clinical medicine is being taught.”
The investigative series reveals that the founders of A4M, Dr. Ronald Klatz and Dr. Bob Goldman, have a conflict of interest with the scientific agenda of A4M since they have financial interests in the very products (e.g. Arasys Perfector) and services (Regenerco) advertised at the associated convention.
But distancing A4M from the kinds of products and services offered at the exposition is somewhat disingenuous. Klatz, Goldman and the company that organizes the meeting itself, Tarsus Group PLC, are deeply involved in some of these same kinds of businesses.
Regenerco, for example, is a Klatz and Goldman company seeking to “offer, at a reasonable cost, high-quality, multi-screened vital pathogen-free stem cells originating from umbilical cords and placentas of healthy, live-births, or autologous [genetically identical] adult stem cells from peripheral blood collection.” It promises to use such cells as an anti-aging therapy and has made a deal with a resort developer in Indonesia, PT Hanno Bali, to be the exclusive stem cell distributor for anti-aging resorts serviced by yet another company called One Life +.
The Arasys Perfector is being funded with up to $500,000 from a firm called CapRegen PLC, a publicly traded regenerative medicine investment company based in the United Kingdom. CapRegen’s founders? Klatz, Goldman and Tarsus Group.
Do the commercial ambitions of the founders of A4M jeopardize the scientific agenda of A4M? What do you think?
Undercover officers have discovered evidence of steroid use at the fitness center and distribution by either Goodman or other members at the fitness center, according to court records.
That evidence includes syringes, bank statements, computer software, cell phone records and financial records belonging to either Goodman or the fitness center.
A confidential informant has told undercover officers that Goodman was “actively distributing steroids” and that “individuals associated with Physical Edge often use and/or distribute steroids,” according to court records.
NPC bodybuilder Keith Koppenhaver, who last competed at the 2000 NPC Junior Nationals, has also been implicated. Koppenhaver was a personal trainer at Physical Edge (Hi-Octane) and a friend of Chris Goodman.
Undercover officers seized several types of steroids, human growth hormone, insulin and other dangerous, controlled substances from Koppenhaver’s home or property, according to court records.
He has admitted to undercover officers that he sold steroids and never pays taxes from those sales or the money that he receives as a personal trainer, according to court records.
He has identified Goodman and a professional bodybuilder in the Oklahoma City area as his steroid suppliers, according to court records.
Tulsa County District Court records filed Wednesday show that officers recently searched the home and found vials of popular muscle-building steroids and human growth hormone. Among the substances found were testosterone, nandrolone decanate and stanozolol.
Also seized were e-mails to Ducasse “instructing him on bodybuilding drug use,” “handwritten notes regarding steroid cycles,” a “weekly steroid use schedule” and “7 pages of clients,” who are believed to be members of Sky Fitness & Wellbeing, 10121 S. Sheridan Road, according to the court records.
An employee at the fitness center said Friday that Ducasse trains clients at the facility.
Authorities searched the bar in January as part of the crash investigation and found steroids and syringes in a filing cabinet.
But steroid ignorance is apparently contagious in Toledo, Ohio permeating the local media, attorneys and courts.
The NBC 24 affiliate in Toledo also misidentified clenbuterol and growth hormone as steroids, lifting a description of the drugs (practically verbatim) from a March 8th report by Laren Weber of the Toledo Blade (”Rodeo Bar owner sentenced for possession of drugs,” April 14).
Authorities searched the bar in Jan. and found steroids and syringes in a filing cabinet. The items found were listed as a blister pack containing nine tablets of Clenbuterol, a bottle with liquid Clenbuterol, several vials of the human growth hormone Jintropin, and a bag of syringes. Clenbuterol is a steroid used in meat production that is banned in the US.
Surely, the ABC 13 affiliate in Toledo would accurately identify clenbuterol and growth hormone, right? Maybe not. (”Rodeo Bar owner behind bars,” April 14)
Police found body building drugs, box syringes, and an illegal steroid at the bar during a search.
One of the owners of the Rodeo Bar and Grill pleaded no contest last month to possessing human growth hormone.
Finally! But CBS goes on to paraphrase Roumaya’s attorney who apparently identifies growth hormone as an anabolic steroid! Dohh!
An attorney for Jon Roumaya said he was trying to lose weight, so he used the steroid.
CBS and ABC affiliates in Toledo also report that the courts apparently suffer from steroid ignorance too. “Random steroid drug testing” was a condition of Roumaya’s sentence (even though anabolic steroids were not involved in the case).
The testosterone:epitestosterone ratio (T:E ratio) test is a commonly used test designed to catch athletes who artificially manipulate their testosterone levels (usually with exogenous testosterone). The T:E ratio is routinely used in doping protocols around the world at all levels of sport.
Unfortunately, the T:E ratio is not very effective. This has been common knowledge among drug tested athletes for some time. Dan Duchaine first alerted athletes decades ago with Victor Conte concurring more recently. Anti-doping experts such as Charles Yesalis and Don Catlin have reluctantly acknowledged that this is true.
It is not very reliable. It is flawed. The T:E ratio test results in a lot of false negatives (athletes use testosterone but don’t get caught) as well as false positives (innocent athletes test positive for steroid use).
A recent study that we learned about on Trust But Verify and reported on at Steroid Report explains why the test is unreliable and ineffective.
It appears that certain genotypes are more likely to have false negatives (athletes use testosterone but don’t get caught)and other genotypes are more likely to have false positives (innocent athletes test positive for steroid use) (”Doping Test in Sports Confounded by Common Genetic Trait,” March 21).
If you’re a genetically gifted athlete (i.e. you lack the gene that produces the enzyme UGT2B17), you can take an whopping injection of at least 360 milligrams of testosterone without getting caught by the testosterone:epitestosterone ratio test (T:E ratio). This testosterone loophole in drug testing has been known by athletes for decades (anecdotally). It is nice to have solid scientific evidence to confirm it.
The 360 mg corresponds to a 500 mg intramuscular injection of testosterone enanthate. Yes, many athletes can take this quantity of the anabolic-androgenic steroid testosterone and still pass current WADA doping controls.
The T:E ratio test discriminates based on the ethnicity of the athlete subjected to the doping protocol. This little bit of information is impossible to overlook.
So, which ethnic groups are most likely to have false negatives on the T:E ratio test?
The latest study suggests as many as 40% of athletes with UGT2B17 homozygous deletion/deletiongenotype can take at least 500 mg of testosterone enanthate and still maintain a 4:1 T:E ratio. The following lists various ethnic groups with the estimated percentage that possess the “doping friendly” genotype (data extracted from here and here).
78.0% - Mulatto (Brazilian)
66.7% - Eastern Asian (Korean)
57.3% - Cape Colored (Cape Town, South Africa)
37.6% - Mexican Mestizo
30.4% - Asian Pacific (Southeast Asian/Southern Chinese, Asian Indian, Japanese)
29.1% - Black (African Americans, African Blacks, South/Central American Blacks)
9.3% - White Caucasian (Swedish)
3.5% - White Caucasian (primarily European)
Yes, athletes with UGT2B17 homozygous deletion/deletiongenotype are much more likely to pass a doping test if they choose to cheat (false negative). And yes, certain ethnic groups are much more likely to possess this genotype.
What should WADA do about this? Is this a problem for professional sports or high school districts that routinely use the T:E ratio test?
Reporters from around the country have descended upon Houston, Texas pursuing their steroid witch hunt against anyone who may have used steroids or could have potentially provided anabolic steroids to Major League Baseball players e.g. Roger Clemens and Andy Pettitte. The targets in their steroid investigation have expanded from fitness professionals Kelly Blair (of 1-on-1 Elite Personal Fitness) and Shaun Kelley (of Shaun Kelley Weight Control) to at least one Houston-area physician.
While the New York Daily News admits they have no evidence that Shaun Kelley provided steroids to Roger Clemens, they do not hesitate to point the finger at Lisa Routh, M.D. of Brainwaves Neuroimaging Clinic in Houston who worked with Shaun Kelley.
Neither does the Daily News have evidence that Dr. Routh prescribed steroids to Roger Clemens or any major league baseball player for that matter. But they seem content to demonize her because she was outspoken in her defense of the use of anabolic steroids in medicine. She admits to prescribing testosterone and growth hormone to policemen, professional wrestlers, and people who work out in an effort to improve their quality of life. Furthermore, Dr. Routh proposed that professional athletes be permitted to use performance enhancing drugs under a doctor’s supervision (”Houston-area gyms part of drug culture beyond sports scope,” March 16).
Interviews with Routh, of the Brainwaves Medical Center in Houston, and with eight former and current employees of Kelley, reveal a corner of the fitness industry where the same drugs that are stigmatizing professional sports are seen simply as a lifestyle choice for others.
Routh told The News that she regularly prescribed testosterone and human growth hormone for a large number of Boston policemen, who “get on a frickin’ plane and come down here twice a year, for frickin’ growth hormone and testosterone.”
She said she prescribes other hormones for menopausal women and professional wrestlers - all in the name of quality of life. Furthermore she argued for legalizing such drugs in professional sports, provided athletes have medical care.
“We pay them ridiculously, because we expect performance, and I think the bottom line is safety,” says Routh, who proposes allowing big-league baseball clubs to contract with five or 10 doctors in every city who would be the only league-approved providers of drugs. Players caught going elsewhere for their ‘roids would get hit with a fine.
“If someone wants to use human growth hormone or a testosterone product, they need to be under a physician’s supervision,” says Routh. “If they buy stuff off the black market or off some gym rat and they’re not under a doctor’s supervision, they should pay a penalty, and they should get the penalty that hurts, in the wallet.”
The Daily News also persists in its efforts to tarnish and incriminate fitness professionals in Houston. They continued their attack on 1-on -1 Elite Personal Fitness (even though Kelly Blair categorically denied their allegations) by reporting that co-owner Kevin Schexnider was prescribed testosterone cypionate and Anadrol by Revolution Medical Center in Phoenix several years ago; further Schexnider knew former bodybuilder Craig Titus who is awaiting trial on murder charges.
Prosecutors have re-opened the case of anti-aging doctor Ramon Scruggs in an effort to find more baseball players who have used anabolic steroids (”Inquiry Into Doctor May Link Players to Drugs,” March 12). In June 2004, Dr. Scruggs was formally accused of prescribing steroids and ancillary medications without justification over the internet to patients who he did not physically examine. He settled his case with the State of California in August 2006.
In the settlement, Scruggs agreed the state could prove the charges and accepted a $4,800 fine and 35 months of probation: during that time he is required to have an outside monitor, take various courses and cease prescribing over the Internet. The settlement was agreed to in August 2006 and took effect in March 2007.
Dr. Scruggs prescribed steroids to professional baseball players Troy Glaus and Scott Schoeneweis in 2003 and 2004. In the fall of 2007, this information was leaked to the media by the office of District Attorney David Soares which is leading the investigation of the steroid scandal involving Signature Pharmacy.
As a result of the leak, prosecutors with the U.S. Attorney’s Office in the Northern District of California want to revisit Scrugg’s case fishing for additional Major League Baseball players who use steroids.
Ramon Scruggs, M.D. is a physician who, prior to his legal troubles, openly worked with bodybuilders visiting his New Hope Med website; he felt that the best way for a physician to effectively supervise the health of a steroid-using bodybuilder was to medically monitor their steroid use and assure that bodybuilders avoided potentially dangerous black market sources of anabolic steroids.
Dr. Scruggs explained his criteria for prescribing steroids to bodybuilders in an interview with Jason Mueller of Anabolic Extreme in 1999-2000.
[T]hey have to do extensive blood work, they have to fill out a very detailed questionnaire, and they have to have a 40-minute to hour interview with me. That’s basically where we decide if someone can do this. Now, I’ll admit to you that as I do this, my criteria have relaxed. Before I would only do this with athletes or with ordinary citizens if they had a limitation, if they were hypogonadal, if they were on the low side of normal on their blood work. I’ve gradually relaxed that to include people who would be quote unquote normal. You’ve got to realize that virtually everything hormonal is considered normal by the establishment. They have virtually no ability to look at, let’s say the estrogen/progesterone levels for a woman, and testosterone for men and women, and say anything much about them at all because everybody from age 12 to age 90 is considered normal.
Dr. Scruggs felt that he was doing the right thing by monitoring and prescribing steroids to bodybuilders.
I feel like I’ve been led along a certain path in life and it’s almost as if I’m supposed to do certain things by fate. I would have, had it been my choice, done things differently from how they’ve actually happened. But I accept that there are no mistakes, which God has us do the things He would have us do, despite what our little self may want, and I feel directed. So yes, I am concerned about it, but at the same time, I know I’m right! I feel very comfortable in the choices I’ve made and the reason for those choices. I know that I’m helping people far more than I’m hurting them. If you want to know the truth, I don’t like taking 22 or 23 year-old and putting them on steroids, it makes me nervous. Yet, I’d rather have them come to me and manage their steroid use, and then have them do it on their own.
Ramon Scruggs has and continues to pay a substantial penalty for having worked with bodybuilders in this capacity, including a Chapter 7 bankruptcy filing in October 2005.
I would expect that most journalists would have a basic understanding of anabolic steroids given that the topic has been a major news story for several years now. But journalists still fail to perform their “steroid fact checking” when writing stories on the topic. The Toledo Blade Newspaper out of Ohio published a story about a steroid bust. The only problem with the story was that the man was not busted for anabolic steroids.
Authorities searched the bar in January and found steroids and syringes in a filing cabinet.
The items found were listed as a blister pack containing nine tablets of Clenbuterol, a bottle with liquid Clenbuterol, several vials of the human growth hormone Jintropin, and a bag of syringes and more human growth hormone. Clenbuterol is a steroid used in meat production that’s banned in the United States.
Clenbuterol is not a steroid and neither is human growth hormone. A substance does not automatically become an anabolic steroid simply because it is used in sports or bodybuilding for performance enhancing purposes. I’m not sure why so many people are committed to remaining blissfully ignorant about steroids. Why the resistance to steroid education?
The New York Times reports that IRS Special Agent Jeff Novitsky is making inquiries about several fitness professionals in the Houston area in an effort to substantiate the use of anabolic steroids and growth hormone by Roger Clemens in a possible federal perjury case. They have asked a former employee about Houston fitness guru Shaun K. Kelley, the owner of Shaun Kelley Weight Control.
Novitzky, who has spent the past five and a half years investigating the distribution of performance-enhancing drugs in professional sports, maintains a lead role in the perjury investigation, the lawyers said, and is interested in questioning a number of people in Houston, including Kelley.
As a result of the New York Times story and Kelley’s implied association with Clemens and performance enhancing drugs, the blogosphere has already started digging up dirt on Shaun Kelley.
Kelley told the New York Post last night on the phone that he never sold performancing enhancing drugs.
“Roger Clemens has never been in my store,” Kelley told The Post in a phone interview last night. “I’ve never sold steroids or growth hormone.” [...]
“That’s all the information these clowns from The Times have,” he said. “That is the weakest report I’ve ever seen printed. If all that they can come up with, they need to find new reporters.
“I will give the FBI a polygraph. I do not deal drugs. I’ve never done anything with Roger Clemens except shake his hand.”
Recently, Kelly Blair, another Houston fitness professional, made national headlines due to his association with MLB baseball player Andy Pettitte and alleged distribution of growth hormone and steroids; the media tried unsuccessfully to find links between Blair and Clemens but settled on trying to link him with a former pro bodybuilder awaiting trial on murder charges.
Obviously, the unwanted attention, unsubstantiated allegations, and government leaks by lawyers close to the investigation are bad for business in Houston fitness industry.
“Like many people who are involved in drugs, they have to pay for that addiction somehow. It appears he’s stolen from his family for years and years,” Lee said.
According to DA Bob Lee, James Edward Moore, Jr’s steroid addiction was so severe that he had to steal significant amounts of money from his father. The District Attorney has filed misdemeanor charges of grand theft and is preparing to file felony charges for theft and identity theft.
“Although often considered similar to abusers of narcotics and other illicit drugs (e.g., heroin or cocaine), non-medical anabolic-androgenic steroid (AAS) users follow carefully planned drug regimens in conjunction with a healthy diet, ancillary drugs and exercise,” said Jack Darkes, a study co-author.
“As opposed to the spontaneous and haphazard approach seen in abusers of psychotropic drugs, everything is strategically planned to maximize benefits and minimize harm.”
James Edward Moore, Jr., was indicted for importation of anabolic steroids and possession with intent to distribute anabolic steroids on February 27, 2008. Moore admitted to ordering steroids from IP China sending money via Western Union on at least six occasions to Zhijum He of China. The charges listed in Moore’s indictment were based on thousands of vials and ampules of steroids and thousands of steroid tablets found at Moore’s residence, storage lockers, and three intercepted packages linked to Moore.
The investigation of Moore began in late August 2007 when the Department of Homeland Security, Customs and Border Protection (CBP) opened an incoming package addressed to Jimmy Moore, Jr.; the steroid shipment was sent via International Express Mail by Sany Zeng of Chungsa, Hunan (China).
A second incoming package from China on October 22, 2007 was examined by federal authorities under an anticipatory search warrant. This International Express Mail shipment contained various anabolic steroids and growth hormone, including products labelled Test 400, British Dragon Trenabol Depot, Primobolan QV 100, Teston QV 200, and HGH marked Getropin 10IU Recombinant Human Growth Hormone.
The third incoming package was ordered from AlinShop and shipped by Gore Elena from the Moldova Republic. It contained eight 5mL sachets containing testosterone cypionate and eight sachets containing testosterone enanthate. All sachets were marked “Aromathekaypoil.”
Moore waived his Miranda Rights and told investigators he sold the anabolic steroids primarily to bodybuilders at the Santa Cruz Gold’s Gym and used them for personal medical problems e.g. “to fix his hormone levels.” He reported that he was disabled due to cardiomyopathy and kidney problems. Due to the sheer quantity of anabolic steroids discovered during the steroid bust, the Gold’s Gym in Santa Cruz has the most “jacked” bodybuilders in the country.
Moore resided at a house for recovering drug and alcohol addicts where he was manager and caretaker of the facility.
